Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)
| Autor: | M Slobodan Jankovic, Dejan Aleksic, M Srđan Stefanović, Z Pavle Petković, N Miloš Milosavljević |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Drug
medicine.medical_specialty drug-drug interactions media_common.quotation_subject Intensive Care Unit Delphi method RM1-950 030226 pharmacology & pharmacy intensive care unit Delphi focus 03 medical and health sciences 0302 clinical medicine Medicine 030212 general & internal medicine Intensive care medicine Stroke media_common business.industry medicine.disease Focus group stroke 3. Good health delphi Therapeutics. Pharmacology Neurological intensive care unit business |
| Zdroj: | Hospital Pharmacology-International Multidisciplinary Journal (2021) 8(2):1041-1050 Hospital Pharmacology, Vol 8, Iss 2, Pp 1041-1050 (2021) |
| ISSN: | 2334-9492 |
| Popis: | Introduction: The clinical significance of potential drug-drug interactions (pDDIs), especially in the intensive care unit (ICU) manifested mostly as adverse drug reactions. Aim: The goal of this research was to conduct a focus group, in which the participants were decisionmakers in acute ischemic stroke patient treatment. Also, the aim was to reach a consensus, due to the Delphi process, between neurologists and clinical pharmacologists regarding this highly vulnerable group of patients. Material and Methods: In this academic research, so-called applied focus group (the goal was to reach practical decisions) and clinical focus group (determining motives, predeterminations, bias, prejudice and analyzing the behavior leading to a certain outcome) was done. Results: Continuing medical education of neurologists is needed regarding pDDIs and the use of an online pDDIs checker. Certain groups of patients with AIS are at particular risk of exposure to pDDIs. Certain drug groups are more likely to interact with other drugs. Conclusions: Defining medical recommendations/guidelines on evidence base medicine about pDDIs in patients with AIS would significantly contribute to reducing their frequency in this vulnerable patient population. |
| Databáze: | OpenAIRE |
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