| Autor: |
W. H. Heidema, J. Van Drongelen, M. E. A. Spaanderman, R. R. Scholten |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Ultrasound in Obstetrics & Gynecology, 62, 1, pp. 122-129 |
| Popis: |
Contains fulltext : 294528.pdf (Publisher’s version ) (Open Access) OBJECTIVE: Obesity and pre-eclampsia (PE) are both associated with vascular dysfunction, which translates into an increased risk for cardiovascular disease in later life. The aim of this study was to investigate whether there is an interaction between body mass index (BMI) and a history of PE in their effects on vascular health. METHODS: This was an observational case-control study of 30 women with a history of PE who were compared with 31 age- and BMI-matched controls who had an uncomplicated pregnancy. Flow-mediated dilation (FMD), carotid intima-media thickness (cIMT) and carotid distensibility (CD) were measured 6-12 months postpartum. To evaluate the impact of physical fitness, maximum oxygen uptake capacity was assessed using a standardized maximum exhaustion cycling test using breath-by-breath analysis. To specify further BMI subgroups, metabolic syndrome constituents were assessed in all individuals. RESULTS: Formerly pre-eclamptic women had significantly lower FMD (5.1 ± 2.1% vs 9.4 ± 3.4%; P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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