Hippocampal Atrophy/Sclerosis Is Associated with Old, Calcified Parenchymal Brain Neurocysticercosis, But Not with More Recent, Viable Infections
| Autor: | Sofía S. Sánchez, Javier A. Bustos, Oscar H. Del Brutto, Genaro Herrera, Antonio Carlos dos Santos, E. Javier Pretell, Isidro Gonzales, Herbert Saavedra, Héctor H. Garcia |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Hippocampal Atrophy/Sclerosis Neurocysticercosis Medial temporal atrophy Parenchymal Brain Neurocysticercosis Hippocampal formation Infections Gastroenterology Hippocampus Article Epilepsy Interquartile range Virology Internal medicine Parenchyma parasitic diseases Medicine Humans Sclerosis medicine.diagnostic_test business.industry urogenital system Calcinosis Neglected Diseases Magnetic resonance imaging medicine.disease Magnetic Resonance Imaging Hippocampal atrophy Infectious Diseases Parasitology Female Atrophy business |
| Zdroj: | Am J Trop Med Hyg |
| Popis: | Magnetic resonance images from 197 patients with calcified neurocysticercosis (NCC), 38 with viable NCC and 197 NCC-free healthy rural villagers were evaluated to compare the frequency of hippocampal atrophy/sclerosis (HAS) across these populations. Scheltens’ medial temporal atrophy scale was used for hippocampal rating. The median age of the 432 study participants was 46 years (interquartile range, 29–62 years), and 58% were women. Hippocampal atrophy/sclerosis was disclosed in 26.9% patients with calcified NCC, compared with 7.9% in patients with viable NCC and 8.1% in healthy rural villagers. After adjusting for age, gender, and history of epilepsy, hippocampal atrophy/sclerosis was more frequent in patients with calcified NCC than in those with viable cysts (RR, 3.60; 95% CI, 1.18– 0.99; P = 0.025) and healthy rural villagers (RR, 3.43; 95% CI, 1.94–6.06; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|