Relationship between Serum Levels of Selenium and Thyroid Cancer: A Systematic Review and Meta-Analysis
| Autor: | Runhua Hao, Ping Yu, Lanlan Gui, Niannian Wang, Da Pan, Shaokang Wang |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Nutrition and Cancer. 75:14-23 |
| ISSN: | 1532-7914 0163-5581 |
| DOI: | 10.1080/01635581.2022.2115082 |
| Popis: | Thyroid cancer is one of the most malignant tumors and a serious threat to human health. Selenium (Se) is an essential trace element that is critical for thyroid function. Since the relationship between Se and thyroid cancer remains unclear, a meta-analysis was performed to clarify the relationship. A total of five databases (PubMed, Web of Science, Scopus, Embase and Cochrane library) were searched for case-control studies and cohort studies on serum levels of Se and thyroid cancer published up to 13 July 2022. Seven articles consisting of 10 case-control studies and comprised of 2,205 subjects met the inclusion criteria for meta-analysis. From the 10 selected studies, pooled analysis indicated that thyroid cancer patients had lower serum levels of Se than healthy controls [standardized mean difference = -1.25, 95% confidence interval = (-2.07, -0.44) |
| Databáze: | OpenAIRE |
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