Vasodilatory capacity of the skin in venous disease and its relationship to transcutaneous oxygen tension
| Autor: | T. R. Cheatle, E. Stibe, P. D. Coleridge Smith, John H. Scurr, S. K. Shami |
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| Rok vydání: | 1991 |
| Předmět: |
Adult
Male medicine.medical_specialty Hot Temperature Vasodilation Microcirculation Varicose Veins Scleroderma Localized Basal (phylogenetics) Internal medicine Varicose veins medicine Humans Lipodermatosclerosis Aged Skin business.industry Lasers Middle Aged Laser Doppler velocimetry Surgery Oxygen Cardiology Female medicine.symptom Varices Complication business Blood Gas Monitoring Transcutaneous |
| Zdroj: | British Journal of Surgery. 78:607-610 |
| ISSN: | 1365-2168 0007-1323 |
| DOI: | 10.1002/bjs.1800780527 |
| Popis: | Low transcutaneous oxygen tension (Ptc,O2) values in the supramalleolar skin of patients with venous disease are often reported. This measurement involves heating the skin to 43°C to cause maximum vasodilatation and is valid only if liposclerotic and normal skin can vasodilate to the same degree. Forty-four limbs were studied, 15 with lipodermatosclerosis (LDS), 14 with uncomplicated varicose veins, and 15 controls. A Ptc,O2 electrode was modified to incorporate a laser Doppler probe. Laser Doppler flux was measured in the supramalleolar skin before and after local heating to 43°C and the relative increase in flux was measured. The Ptc,O2 was then measured at the same site and on the chest. Vasodilatory capacity was expressed as the ratio of peak:basal laser Doppler flow, and the Ptc,O2 was expressed as a leg:chest ratio. Median laser Doppler flow was higher in limbs with LDS (median 67 mV) than in normal limbs (median 40 mV) (P |
| Databáze: | OpenAIRE |
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