Extracorporeal membrane oxygenation: the MOTOR of cytokine production?

Autor: Seiko Hayakawa, Taku Miyasho, Osamu Nishida, N Yasuoka, Naohide Kuriyama, Miho Yumoto, Junpei Shibata, Yoshitaka Hara, Kazuhiro Moriyama, S Yamada, Tomoyuki Nakamura, Yasuyo Shimomura, M. Ito, Sohta Uchiyama, Chizuru Yamashita, K Kawata
Rok vydání: 2013
Předmět:
Zdroj: Critical Care
ISSN: 1364-8535
Popis: The usefulness of extracorporeal membrane oxygenation (ECMO) is being rediscovered in the wake of the pandemic of H1N1 influenza. However, it has been reported that patients who received ECMO often developed virus-associated hemophagocytic syndrome (VAHS), compared with those without ECMO support. Although there is ample evidence that extensive cytokine activation is a key factor in VAHS, ECMO itself could be a potential trigger to exacerbate the pathology by amplifying cytokine activation. In this study, we investigated whether mediators such as cytokines may be produced by ECMO.
Databáze: OpenAIRE