Manifestation of Coronary Atherosclerosis in Klang Valley, Malaysia: An Autopsy Study
| Autor: | Norizal Mohd Noor, Effat Omar, Mohd Shah Mahmood, Mansharan Kaur Chainchel Singh, R Rahimi, Shahidan Md Noor, Hapizah Nawawi, Nurliza Abdullah |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Population Autopsy Coronary Artery Disease 030204 cardiovascular system & hematology Sudden death Sudden cardiac death Coronary artery disease Young Adult 03 medical and health sciences 0302 clinical medicine Cause of Death Internal medicine Epidemiology Internal Medicine medicine Humans 030216 legal & forensic medicine education Coronary atherosclerosis Aged Cause of death education.field_of_study business.industry Biochemistry (medical) Malaysia Middle Aged Prognosis Cardiovascular disease medicine.disease Survival Rate Cross-Sectional Studies Death Sudden Cardiac Cardiology Female Original Article Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | Journal of Atherosclerosis and Thrombosis |
| ISSN: | 1880-3873 1340-3478 |
| Popis: | Aims: The present study aimed to determine the epidemiological aspects of medico-legal autopsies and manifestation of coronary atherosclerosis. Methods: This was a cross sectional study involving 222 cases recruited from National Institute of Forensic Medicine (NIFM) Hospital Kuala Lumpur (HKL) and Department of Forensic Medicine Hospital Sungai Buloh (HSgB) for a period of 15 months, from December 2012 to April 2014. Sociodemographic and autopsy findings, including the cause and manner of death were documented. Results: Male and female subjects aged 18–70 years were recruited. Males contributed to 86% of the total subjects and comprised 61% of young adults. Road traffic accidents were the primary cause of death, contributing almost 50% of the subjects. One third of the cases comprised of death due to natural causes, wherein almost 75% of the subjects within this category succumbed to sudden cardiac death. Coronary artery disease (CAD) contributed to 60% of the sudden cardiac death (SCD). Single and double-vessel diseases were the most common pattern of atherosclerosis. In almost 80% of CAD cases, atherosclerosis affected the left anterior descending artery (LAD). Conclusion: Cardiovascular diseases were the most significant natural cause of sudden death with a staggering figure of 75%. CAD was the single most commonly encountered pathology within the SCD. Most cases presented with single and double-vessel diseases, observed in all subjects, as well as the young adult population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|