An Overview of the Efficacy of a Next Generation Electroceutical Wound Care Device
| Autor: | Greggory Housler, Soon S. Park, Sue Cross, Mina Izadjoo, Vanessa Marcel, Hosan Kim |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Wound site medicine.medical_specialty Medical device Silver Electrochemotherapy Polyesters 030207 dermatology & venereal diseases 03 medical and health sciences Wound care 0302 clinical medicine Medicine Humans Wound Healing Electric Power Supplies integumentary system business.industry Public Health Environmental and Occupational Health General Medicine Biocompatible material Bandages Surgery Zinc 030104 developmental biology Treatment modality Biofilms Wound Infection business Wound healing Biomedical engineering Voltage |
| Zdroj: | Military medicine. 181 |
| ISSN: | 1930-613X |
| Popis: | Novel approaches including nonpharmacological methodologies for prevention and control of microbial pathogens and emerging antibiotic resistance are urgently needed. Procellera is a wound care device consisting of a matrix of alternating silver (Ag) and zinc (Zn) dots held in position on a polyester substrate with a biocompatible binder. This electroceutical medical device is capable of generating a direct current voltage (0.5-0.9 Volts). Wound dressings containing metals such as Ag and/or Zn as active ingredients are being used for control of colonized and infected wounds. Reports on the presence of electric potential field across epithelium and wound current on wounding have shown that wound healing is enhanced in the presence of an external electrical field. However, majority of the electrical devices require an external power source for delivering pulsed or continuous electric power at the wound site. A microelectric potential-generating system without an external power source is an ideal treatment modality for application in both clinical and field settings. The research presented herein describes efficacy evaluation of a wireless bioelectric dressing against both planktonic and biofilm forms of wound pathogens including multidrug resistant organisms. |
| Databáze: | OpenAIRE |
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