Effects of local anaesthetics on retinal spreading depression
| Autor: | H. Martins-Ferreira, S. R. Chebabo, R. J. do Carmo |
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| Rok vydání: | 1993 |
| Předmět: |
Slow potential
Retina Dose-Response Relationship Drug Lidocaine Chemistry Local anesthetic medicine.drug_class Benzocaine General Neuroscience Retinal In Vitro Techniques Blockade chemistry.chemical_compound medicine.anatomical_structure Cortical spreading depression Anesthesia medicine Animals sense organs Chickens Evoked Potentials medicine.drug |
| Zdroj: | Experimental Brain Research. 96 |
| ISSN: | 1432-1106 0014-4819 |
| DOI: | 10.1007/bf00227115 |
| Popis: | This study examines the effect of two local anaesthetics, benzocaine and lidocaine, on propagation, amplitude and duration of the slow potential change of spreading depression. The experiments were performed in isolated chick retina superfused with Ringer's solution. We observed, for both drugs, a dose-related decrease in all parameters analysed. The maximal effect on propagation was blockade of the reaction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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