More insights into the immunosuppressive potential of tumor exosomes
| Autor: | Paola Filipazzi, Stefano Fais, Veronica Huber, Licia Rivoltini, Manuela Iero |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Medicine(all)
Tumor microenvironment business.industry Biochemistry Genetics and Molecular Biology(all) Disease progression lcsh:R lcsh:Medicine General Medicine Tumor immunity General Biochemistry Genetics and Molecular Biology Microvesicles Cell biology Immune tolerance Immune system Cancer cell Alternative complement pathway Medicine business |
| Zdroj: | Journal of Translational Medicine, Vol 6, Iss 1, p 63 (2008) |
| ISSN: | 1479-5876 |
| Popis: | If tumor cells are known to affect immune functions through a series of different strategies mostly relying on the release of soluble suppressive molecules, their ability of using suppressive membrane vesicles, the so called exosomes, to mould tumor microenvironment has been so far rather neglected. Here we want to gather attention on this alternative pathway of intercellular cross-talk, discussing the possible implications in tumor immunity and disease progression, and shedding light into the potential ways to counteract exosomes release by cancer cells. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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