Sleep is associated with reduction of epileptiform discharges in benign adult familial myoclonus epilepsy

Autor: Morito Inouchi, Kazuo Chin, Yuko Nakayama, Riki Matsumoto, Hirofumi Takeyama, Shamima Sultana, Masao Matsuhashi, Akihiro Shimotake, Takefumi Hitomi, Akio Ikeda, Ryosuke Takahashi, Takeshi Inoue, Katsuya Kobayashi
Rok vydání: 2019
Předmět:
0301 basic medicine
nCPAP
nasal continuous positive airway pressure
REM
rapid eye movement
EMG - Electromyography
Polysomnography
ADCME
autosomal dominant cortical tremor
myoclonus
and epilepsy
Irritability
Article
lcsh:RC321-571
03 medical and health sciences
Behavioral Neuroscience
BAFME
benign adult familial myoclonus epilepsy
0302 clinical medicine
Benign adult familial myoclonus epilepsy
Benign adult familial myoclonus epilepsy (BAFME)
medicine
PSG
polysomnography
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
ULD
Unverricht-Lundborg disease
Light sleep
Sleep Stages
medicine.diagnostic_test
business.industry
Epileptiform discharges
Mean age
Sleep in non-human animals
nervous system diseases
030104 developmental biology
Neurology
Anesthesia
FCMTE
familial cortical myoclonic tremor with epilepsy
Neurology (clinical)
medicine.symptom
Effects of sleep modification on cortical irritability
business
EMG
electromyography
EEG
electroencephalography
030217 neurology & neurosurgery
Zdroj: Epilepsy and Behavior Case Reports, Vol 11, Iss, Pp 18-21 (2019)
Epilepsy & Behavior Case Reports
ISSN: 2213-3232
DOI: 10.1016/j.ebcr.2018.09.010
Popis: To clarify the effects of sleep on cortical irritability in benign adult familial myoclonus epilepsy (BAFME), we retrospectively compared epileptiform discharges of electroencephalographies (EEGs) between awake and sleep periods in 5 patients (mean age: 49.6 ± 20.3 years). We also analyzed polysomnography (PSG) of 1 patient. Epileptiform discharges were significantly more frequent during the awake period (1.3 ± 1.2/min) than those during light sleep stages (0.02 ± 0.04/min) (P
Highlights • We retrospectively analyzed the number of epileptiform discharges in BAFME. • Epileptiform discharges were more frequent during awake period in BAFME. • Our study indicated a reduction in cortical irritability during sleep in BAFME. • BAFME and Unverricht-Lundborg disease may share a similar phenomenological mechanism.
Databáze: OpenAIRE
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