Maternal and paternal diversity in Xinjiang Kazakh population from China
| Autor: | A. Abulimiti, H. Hao, K. Chen, W. Shan, Z. Ma, W. Wu, X. Zheng, F. Zhang, Zh. Ren |
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| Rok vydání: | 2015 |
| Předmět: |
Genetic Markers
Male education.field_of_study Genetic diversity China Chromosomes Human Y Polymorphism Genetic Haplotype Population General Medicine Kazakh Biology DNA Mitochondrial language.human_language Gene flow Haplotypes Evolutionary biology Genetic marker Genetic variation language Humans Female education |
| Zdroj: | Genetika. 50(11) |
| ISSN: | 0016-6758 |
| Popis: | The ancient silk road of China passed through Xinjiang and facilitated gene exchanges from the East and the West which impacted on the genetic variation and structure of the nomadic Kazakh population residing there. In order to understand the nature of this genetic variation; 151 Xinjiang Kazakh samples were obtained from four main Kazakh groups and were analyzed using mtDNA and Y-chromosome markers. The Xinjiang Kazakh population is heterogeneous, showing the coexistence of matrilineal lineages with different origins. No genetic differentiation of mtDNA is observed among the four different regional Xinjiang Kazakh populations in Xinjiang by AMOVA and Networks. The genetic diversity of Y-STR loci is higher in Xinjiang Kazakhs (0.968 ± 0.014) than the Kazakhs from Kazakhstan (0.629 ± 0.071) and Russia (0.835 ± 0.020). East Eurasians make a more than 50% contribution to the maternal and paternal lineages of Xinjiang Kazakhs. There is more gene flow from West Eurasian into the maternal lineages of Xinjiang Kazakh than to the Kazakhs from Russia and Kazakhstan. Moreover, mtDNA and Y-STR displayed high polymorphism in Xinjiang Kazakhs (the haplotype diversity and power of discrimination were 0.990 ± 0.003, 0.9137 for mtDNA HVS and 0.968 ± 0.014, 0.9489 for Y-STR system, respectively), suggesting they would be very useful and important markers for forensic analysis and population genetic studies. |
| Databáze: | OpenAIRE |
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