A Case of Early Stage Bladder Carcinosarcoma in Late Recurrence of Urothelial Carcinoma after Transurethral Resection
Autor: | Yoshiaki Kusumi, Daisaku Hirano, Shou Ohno, Fuminori Sakurai, Toshiyuki Yoshida, Daigo Funakoshi |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
Urinary bladder medicine.diagnostic_test business.industry Pirarubicin 030232 urology & nephrology Urology Case Report General Medicine Cystoscopy medicine.disease lcsh:Diseases of the genitourinary system. Urology lcsh:RC870-923 Resection 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Carcinosarcoma medicine Immunohistochemistry Myocardial infarction Stage (cooking) business medicine.drug |
Zdroj: | Case Reports in Urology, Vol 2018 (2018) Case Reports in Urology |
ISSN: | 2090-6978 |
Popis: | Carcinosarcomas of the urinary bladder are rare biphasic neoplasms, consisting of both malignant epithelial and malignant mesenchymal components, and the prognosis of this tumor is unfavorable in most patients with even possibility of resection of disease. A 77-year-old male with a history of transurethral resection (TUR) of urothelial carcinoma (UC) of the bladder and adjuvant intravesical chemotherapy with pirarubicin 10 years ago revisited our department with a gross hematuria. Cystoscopy demonstrated an approximately 2.5 cm nonpapillary tumor on the right wall of the bladder. Pelvic MRI showed the tumor without extending the base of the bladder wall. The tumor could be completely removed with TUR. The malignant epithelial elements consisted of high-grade UC and the majority of mesenchymal components were fibrosarcomatous differentiation based on immunohistochemical studies. The tumor could be pathologically also suspected to be an early stage on TUR specimens. Although he has received no additional intervention due to the occurrence of myocardial infarction at three weeks after the TUR, he has been alive with no evidence of recurrence of the disease 27 months after the TUR. Some early stages of bladder carcinosarcoma might have a favorable prognosis without aggressive treatments. |
Databáze: | OpenAIRE |
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