Risk assessment of mortality from acute exposure to ambient fine particles based on the different toxicities of chemical compositions in China

Autor: Tao Xue, Bo Zheng, Xin Li, Yuxuan Zhang
Přispěvatelé: Beijing Technology and Business University, Tsinghua University [Beijing] (THU), Peking University [Beijing], Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Max Planck Institute for Chemistry (MPIC), Max-Planck-Gesellschaft, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
different toxicities
Total risk
010504 meteorology & atmospheric sciences
Fine particulate
Air pollution
010501 environmental sciences
medicine.disease_cause
fine particles
01 natural sciences
complex mixtures
Adverse health effect
Environmental health
11. Sustainability
medicine
GE1-350
[SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces
environment

Disease burden
elemental carbon
0105 earth and related environmental sciences
General Environmental Science
[SDU.OCEAN]Sciences of the Universe [physics]/Ocean
Atmosphere

health risk
Renewable Energy
Sustainability and the Environment

Public Health
Environmental and Occupational Health

source apportionment
3. Good health
Environmental sciences
13. Climate action
Acute exposure
Environmental science
Risk assessment
Multivariate gaussian model
Zdroj: Journal of Integrative Environmental Sciences
Journal of Integrative Environmental Sciences, Taylor & Francis, 2021, 18 (1), pp.55-66. ⟨10.1080/1943815X.2021.1912106⟩
Journal of Integrative Environmental Sciences, 2021, 18 (1), pp.55-66. ⟨10.1080/1943815X.2021.1912106⟩
Journal of Integrative Environmental Sciences, Vol 18, Iss 1, Pp 55-66 (2021)
ISSN: 1943-815X
DOI: 10.1080/1943815X.2021.1912106⟩
Popis: Health risks, including mortalities and morbidities, attributed to chronic or acute exposure to ambient fine particulate matter (PM2.5), have been assessed based on the increments in ambient concentrations. Different toxicities of the various chemical compositions in PM2.5 mixtures have been confirmed by epidemiological evidence but have rarely been considered. We proposed an approach to calculate the disease burden of both the chemical components and concentrations of PM2.5 by combining their pre-established dose–response relationships with a multivariate Gaussian model. We estimated that PM2.5 mixtures account for 0.43 (95% CI: 0.29 ~ 0.56) million premature deaths in China in 2013, consistent with estimates based on single-pollutant models in quantifying the total risk but with differing risk distributions. The residential, an elemental carbon-rich emission sector, accounted for approximately a quarter of PM2.5 emissions, but for half of the premature deaths attributable to air pollution, due to the stronger toxicity of carbonaceous particles than other PM2.5 compositions. Conventional risk assessments based on PM2.5 mass assume equality in the toxicity of PM2.5 compositions and may therefore fundamentally underestimate the skewness of the risk distribution and the adverse health effects of particles from the residential emissions. The different toxicities of the of PM2.5 compositions modify the risk estimates and thus should be included in emission reduction plans.
Databáze: OpenAIRE