A MODIFIED FILTER PAPER CULTURE TECHNIQUE FOR SCREENING OF STRONGYLOIDES STERCORALIS IVERMECTIN SENSITIVITY IN CLINICAL SPECIMENS
| Autor: | Porntip Laummaunwai, Thidarat K. Prasongdee, Saree Singthong, Kittisak Sawanyawisuth, Pewpan M. Intapan, Wanchai Maleewong |
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| Rok vydání: | 2006 |
| Předmět: |
Paper
Drug Ivermectin Antiparasitic Agents Filter paper biology business.industry media_common.quotation_subject Drug resistance biology.organism_classification Antiparasitic agent Strongyloides stercoralis Infectious Diseases Virology Immunology Animals Medicine Parasitology Sensitivity (control systems) Anthelmintic business medicine.drug media_common |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene. 75:563-564 |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.2006.75.563 |
| Popis: | An in vitro test for the detection of ivermectin sensitivity of Strongyloides stercoralis in human clinical specimens was developed. The test has a simple procedure that combines parasite culture with a drug assay. It is based on the principle of the drug effect on larval development test, combined with a modified coproculture using the filter paper culture technique. This does not require parasite isolation, and drug sensitivity can be shown in relationship to the dose. This test can be applied in field surveys for anthelmintic sensitivity and for appropriate drug rotation strategies when drug resistance occurs. |
| Databáze: | OpenAIRE |
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