The effect of aspirin on the exercise-induced changes in platelet function and blood coagulation
| Autor: | D A Lederer, J.A. Davies, G.P. McNicol, T. Davies |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Blood Platelets
Male medicine.medical_specialty Platelet Aggregation Platelet aggregation Physical Exertion Enzyme Reactivators Platelet Adhesiveness Internal medicine medicine Humans Thromboembolic disease Platelet Mean platelet volume Blood Coagulation Clinical Trials as Topic Aspirin Factor VIII medicine.diagnostic_test business.industry Plasminogen Hematology Blood Cell Count Endocrinology Coagulation Immunology Prothrombin Time Collagen business Partial thromboplastin time medicine.drug |
| Zdroj: | Thrombosis Research. 5:69-81 |
| ISSN: | 0049-3848 |
| DOI: | 10.1016/0049-3848(74)90110-8 |
| Popis: | In a study of 10 normal subjects, administration of aspirin was shown to prevent exercise-induced increases in platelet aggregation to collagen and adrenaline. The exercise-induced rise in the plasminogen-activator content of plasma euglobulin precipitates was also reduced by aspirin, whereas rises in platelet count, factor VIII levels and decrease in partial thromboplastin time of plasma were unaffected. The prevention by aspirin of exercise induced increases in platelet aggregation, in the light of the possible involvement of platelets in thromboembolic disease, suggest that further study of the therapeutic usage of aspirin in treatment of this disease is merited. |
| Databáze: | OpenAIRE |
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