Cytoskeletal biophysics: Passive crosslinker adapts to keep microtubule bundles on track
Autor: | Mary Williard Elting |
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Rok vydání: | 2021 |
Předmět: |
0301 basic medicine
Biophysics technology industry and agriculture Spindle Apparatus macromolecular substances Biology Microtubule sliding Microtubules General Biochemistry Genetics and Molecular Biology Spindle apparatus 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Microtubule General Agricultural and Biological Sciences Cytoskeleton Mitosis 030217 neurology & neurosurgery |
Zdroj: | Current Biology. 31:R793-R796 |
ISSN: | 0960-9822 |
DOI: | 10.1016/j.cub.2021.04.065 |
Popis: | Summary Assembly of the mitotic spindle requires dynamic adaptation and coordination among an array of motors and crosslinkers. A new study demonstrates in vitro how the mitotic crosslinker PRC1 can tune its behavior to regulate the speed of microtubule sliding. |
Databáze: | OpenAIRE |
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