Preliminary outcomes of the European multicentre experience with the ZSI 375 artificial urinary sphincter for treatment of stress urinary incontinence in men
| Autor: | Christophe Llorens, Piotr Chlosta, Manuel Fernández Arjona, Tobias Pottek, Waldemar Różański, Oscar Selvaggio, Frank Neugart, Francesco Iori, Tomasz Golabek, Burkhard von Heyden, Janusz Ciechan, Mikolaj Przydacz, Wojciech Dyś, Giuseppe Carrieri, Emil Śledź, Steve Foley, Mariusz Blewniewski, Bob Yang, Ireneusz Ostrowski |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment 030232 urology & nephrology Urinary incontinence male urinary incontinence Artificial urinary sphincter 03 medical and health sciences 0302 clinical medicine Patient age Prostate medicine Original Paper business.industry Prostatectomy General Medicine artificial urinary sphincter radical prostatectomy High-intensity focused ultrasound Surgery medicine.anatomical_structure 030220 oncology & carcinogenesis Cuff Zephyr Surgical Implants medicine.symptom Complication business |
| Zdroj: | Central European Journal of Urology |
| Popis: | Introduction The ZSI 375 is a new artificial urinary sphincter utilised in men suffering from stress urinary incontinence (SUI). We present the first European multicentre study on the effectiveness of ZSI 375. Material and methods This study was conducted in a retrospective, non-randomized format in centres across Europe. Between May 2009 and December 2014, ZSI 375 was fitted in 109 SUI patients following radical prostatectomy, transurethral resection of prostate (TURP), rectal surgery and high intensity focused ultrasound (HIFU). Patients with history of pelvic radiotherapy or previous surgical treatment for incontinence or stricture were excluded from the series. Follow-up was completed by December 2016. The key outcome measures included overall improvement and complication rates. Results A total of 109 patients in 10 European centres were recruited and had the ZSI 375 device implanted. The average patient age was 72 years old. The indication for the majority of patients was incontinence following radical prostatectomy (100/109 patients, 91.74%). On average, patients were incontinent for 48.6 months prior to treatment. All patients used ≥4 pads daily at baseline and thus were classified as suffering from 'severe incontinence'. The average follow-up until the final visit was 43 months. The pad usage decreased to 0.84 on average by the last visit. There were no reported cases of device infection. A total of 9 patients had urethral cuff erosion (8.25%),which was the most common complication in this series. A further 3 men (2.75%) experienced mechanical failure requiring subsequent device reimplantation. The implantation of the ZSI 375 device was considered successful in 92.66% of patients. Conclusions The ZSI 375 is an effective surgical treatment option in men with severe stress urinary incontinence. |
| Databáze: | OpenAIRE |
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