Family burden of hospital-managed pediatric atopic dermatitis: a nationwide registry-based study
| Autor: | Miriam C. Fenton, Catherine Droitcourt, Jacob P. Thyssen, Yuki M.F. Andersen, Dimittry Delevry, Ida Vittrup, Lone Skov, Alexander Egeberg |
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| Přispěvatelé: | Copenhagen University Hospital, Recherche en Pharmaco-épidémiologie et Recours aux Soins (REPERES), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP), CHU Pontchaillou [Rennes], Regeneron Pharmaceuticals [Tarrytown], Syneos Health [Wilmington], The study was sponsored by Sanofi and Regeneron Pharmaceuticals, Inc., Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty family [SDV]Life Sciences [q-bio] Immunology Adjustment disorders Eczema Dermatitis Atopic 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Quality of life medicine Immunology and Allergy Humans 030212 general & internal medicine Registries Medical prescription Child pain disorder Socioeconomic status Depression (differential diagnoses) Pain disorder atopic dermatitis business.industry Atopic dermatitis medicine.disease Hospitals drug prescriptions mental disorders mothers Pediatrics Perinatology and Child Health depression Quality of Life Anxiety Female medicine.symptom business |
| Zdroj: | Pediatric Allergy and Immunology Pediatric Allergy and Immunology, Wiley, 2021, ⟨10.1111/pai.13693⟩ Pediatric Allergy and Immunology, 2022, 33 (1), ⟨10.1111/pai.13693⟩ Vittrup, I, Droitcourt, C, Andersen, Y M F, Skov, L, Egeberg, A, Delevry, D, Fenton, M C & Thyssen, J P 2022, ' Family burden of hospital-managed pediatric atopic dermatitis : A nationwide registry-based study ', Pediatric Allergy and Immunology, vol. 33, no. 1, e13693 . https://doi.org/10.1111/pai.13693 |
| ISSN: | 0905-6157 1399-3038 |
| DOI: | 10.1111/pai.13693⟩ |
| Popis: | International audience; BACKGROUND: Parents of children with atopic dermatitis (AD) report reduced quality of life and higher stress level, which could increase risk of psychiatric and pain disorders, and medication use. METHODS: By use of Danish national registries, we identified family members of all first-born Danish children born between January 1(st) , 1995 and December 31(st) , 2013 with a hospital diagnosis of AD, matched them 1:10 with family members of children without AD, and followed the cohorts over time. RESULTS: Mothers of children with hospital-managed AD had higher risk of filling a prescription for medications for depression, anxiety, pain and sleep problems, and of consulting a psychologist, but most associations disappeared after full adjustment. Siblings had higher risk of receiving a diagnosis for adjustment disorder, and fathers showed increased risk of filling a prescription for pain medication and of divorce, in crude but not adjusted models. CONCLUSIONS: The increased risk of study endpoints seen in mothers of children with hospital-managed AD was not explained by pediatric AD alone. Rather, the total burden in these families including parent and child morbidity and socioeconomic resources seem to explain these observations. The burden in families of children with AD may potentially affect the overall management of their child’s AD. |
| Databáze: | OpenAIRE |
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