Specific IgG for cat allergens in patients with allergic conjunctivitis

Autor: Tatsuya Mimura, Aki Kondo, Mari Goto, Hiroko Okuma, Anri Miyama, Masao Matsubara, Yusuke Saito, Hidetaka Noma, Yuko Kamei
Rok vydání: 2014
Předmět:
Zdroj: International Ophthalmology. 35:575-586
ISSN: 1573-2630
0165-5701
DOI: 10.1007/s10792-014-9987-8
Popis: Immunoglobulin G (IgG) antibodies are involved in type II and type III hypersensitivity. We evaluated the relation between perennial allergic conjunctivitis and serum levels of specific IgG for cat allergens. A prospective study was conducted in patients with seasonal allergic conjunctivitis (seasonal group, n = 10), patients with perennial allergic conjunctivitis (perennial group, n = 10), and healthy control subjects (control group, n = 10). Serum levels of specific IgE and IgG for cat allergens and total tear IgE were measured, and a skin prick test was also performed. In addition, a severity score associated with allergic conjunctivitis was calculated (0–30). The positive rates and scores of for total tear IgE, serum cat-specific IgE, and serum cat-specific IgG were all higher in the seasonal and perennial groups than in the control group (all p
Databáze: OpenAIRE