Swall-E: A robotic in-vitro simulation of human swallowing

Autor: Nicolas Perrin, Fabrice Neveu, Nihal Engin Vrana, Yo Fujiso, Julian van der Giessen, Virginie Woisard
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Larynx
Male
Physiology
Respiratory System
Silicones
Video Recording
030218 nuclear medicine & medical imaging
User-Computer Interface
0302 clinical medicine
Medicine and Health Sciences
Medicine
Physiological function
Multidisciplinary
Ingestion
Pharyngeal swallowing
digestive
oral
and skin physiology
Robotics
Equipment Design
Healthy Volunteers
Chemistry
medicine.anatomical_structure
Physical Sciences
Engineering and Technology
030211 gastroenterology & hepatology
Anatomy
Robots
Research Article
Adult
Epiglottis
Science
Throat
03 medical and health sciences
Young Adult
Esophagus
Swallowing
stomatognathic system
Tongue
otorhinolaryngologic diseases
Humans
Mouth
business.industry
Mechanical Engineering
Pharynx
Chemical Compounds
Biology and Life Sciences
Deglutition
Gastrointestinal Tract
business
Physiological Processes
Tomography
X-Ray Computed
Digestive System
Actuators
Neck
Biomedical engineering
Zdroj: PLoS ONE
PLoS ONE, Vol 13, Iss 12, p e0208193 (2018)
ISSN: 1932-6203
Popis: Swallowing is a complex physiological function that can be studied through medical imagery techniques such as videofluoroscopy (VFS), dynamic magnetic resonance imagery (MRI) and fiberoptic endoscopic evaluation of swallowing (FEES). VFS is the gold standard although it exposes the subjects to radiations. In-vitro modeling of human swallowing has been conducted with limited results so far. Some experiments were reported on robotic reproduction of oral and esophageal phases of swallowing, but high fidelity reproduction of pharyngeal phase of swallowing has not been reported yet. To that end, we designed and developed a robotic simulator of the pharyngeal phase of human swallowing named Swall-E. 17 actuators integrated in the robot enable the mimicking of important physiological mechanisms occurring during the pharyngeal swallowing, such as the vocal fold closure, laryngeal elevation or epiglottis tilt. Moreover, the associated computer interface allows a control of the actuation of these mechanisms at a spatio-temporal accuracy of 0.025 mm and 20 ms. In this study preliminary experiments of normal pharyngeal swallowing simulated on Swall-E are presented. These experiments show that a 10 ml thick bolus can be swallowed by the robot in less than 1 s without any aspiration of bolus material into the synthetic anatomical laryngo-tracheal conduit.
Databáze: OpenAIRE
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