Ethnic differences in incidence of stroke: prospective study with stroke register
| Autor: | Ruth Dundas, JA Stewart, Charles D.A. Wolfe, Robert Howard, Anthony Rudd |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Age adjustment Population Ethnic origin Risk Factors London Case fatality rate Epidemiology medicine Humans Prospective Studies Registries education Stroke Aged General Environmental Science Aged 80 and over education.field_of_study business.industry Incidence Incidence (epidemiology) General Engineering General Medicine Middle Aged medicine.disease Confidence interval Surgery Cerebrovascular Disorders Social Class Papers General Earth and Planetary Sciences Female business Demography |
| Zdroj: | Europe PubMed Central |
| ISSN: | 1468-5833 0959-8138 |
| DOI: | 10.1136/bmj.318.7189.967 |
| Popis: | To identify ethnic differences in the incidence of first ever stroke.A prospective community stroke register (1995-6) with multiple notification sources. Pathological classification of stroke in all cases was based on brain imaging or necropsy data. Rates were standardised to European and world populations and adjusted for age, sex, and social class in multivariate analysis.A multi-ethnic population of 234 533 in south London, of whom 21% are black.612 strokes were registered. The crude annual incidence rate was 1.3 strokes per 1000 population per year (95% confidence interval 1.20 to 1.41) and 1.25 per 1000 population per year (1.15 to 1.35) age adjusted to the standard European population. Incidence rates adjusted for age and sex were significantly higher in black compared with white people (P0.0001), with an incidence rate ratio of 2.21 (1.77 to 2.76). In multivariable analysis increasing age (P0.0001), male sex (P0.003), black ethnic group (P0.0001), and lower social class (P0.0001) in people aged 35-64 were independently associated with an increased incidence of stroke.Incidence rates of stroke are higher in the black population; this is not explained by confounders such as social class, age, and sex. Ethnic differences in genetic, physiological, and behavioural risk factors for stroke require further elucidation to aid development of effective strategies for stroke prevention in multi-ethnic communities. |
| Databáze: | OpenAIRE |
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