West Nile Virus Neuroinvasive Disease Accelerating Probable Dementia With Lewy Bodies
| Autor: | Evelyne Maillart, Alexander Van Ranst, Kurt Segers, Gerald Glibert, Alionka Bostan, Bernard Dachy, Philippe Clevenbergh |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Lewy Body Disease
Male Fever West Nile virus animal diseases viruses medicine.disease_cause Virus Clonazepam Behavior disorder Neuroinvasive disease mental disorders medicine Humans Cognitive Dysfunction Confusion GABA Modulators Aged Dementia with Lewy bodies business.industry virus diseases medicine.disease Virology Republic of North Macedonia Sciences biomédicales nervous system diseases Psychiatry and Mental health Clinical Psychology Synuclein Encephalitis Geriatrics and Gerontology business Gerontology West Nile Fever |
| Zdroj: | Alzheimer disease and associated disorders, 35 (3 |
| Popis: | We describe a case of dementia with Lewy bodies immediately following encephalitis due to West Nile virus (WNV). The patient had rapid eye movement-sleep behavior disorder and constipation before the onset of encephalitis, which suggests that he would have ultimately developed dementia with Lewy bodies even without WNV infection. Our case illustrates the interactions between α-synuclein and WNV, as observed in mouse models, wherein synuclein expression augments after WNV infection and protects neurons against the virus. info:eu-repo/semantics/published |
| Databáze: | OpenAIRE |
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