Six-month outcomes of corneal crosslinking with dextran-free isotonic riboflavin solution
| Autor: | Gunhal Satirtav, Meryem Donbaloğlu, Ahmet Ozkagnici, Hurkan Kerimoglu, Mehmet Okka, Refik Oltulu, Mehmet Kemal Gündüz, Adnan Karaibrahimoğlu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Time Factors Visual acuity Adolescent genetic structures Raios ultravioleta Riboflavin Treatment outcome Visual Acuity Riboflavina/uso terapêutico Keratoconus Statistics Nonparametric Cornea Young Adult Cross-linking reagents 03 medical and health sciences 0302 clinical medicine lcsh:Ophthalmology Dextranos Isotonic Humans Retrospective Studies Photosensitizing Agents Chemistry business.industry Acuidade visual Corneal Topography Reproducibility of Results Dextrans General Medicine Riboflavin/therapeutic use eye diseases Córnea Ophthalmology Cross-Linking Reagents Treatment Outcome lcsh:RE1-994 Ultraviolet rays 030221 ophthalmology & optometry Colágeno Female Collagen Isotonic Solutions Nuclear medicine business 030217 neurology & neurosurgery Reagentes para ligações cruzadas |
| Zdroj: | Arquivos Brasileiros de Oftalmologia, Vol 79, Iss 3, Pp 147-150 (2016) Arquivos Brasileiros de Oftalmologia v.79 n.3 2016 Arquivos brasileiros de oftalmologia Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO |
| ISSN: | 1678-2925 |
| Popis: | Purpose: To analyze the short-term clinical and topographic outcomes in patients with keratoconus after corneal collagen cross-linking treatment (CXL) with dextran-free isotonic riboflavin solution. Methods: In this retrospective case series, 26 eyes from 26 patients with keratoconus were studied. The best corrected visual acuity (BCVA) and refractive and topographic findings were analyzed at a 6-month follow-up. Results: The mean BCVA (Snellen lines) values before and 1, 3, and 6 months after CXL were 0.51 ± 0.2, 0.48 ± 0.2, 0.57 ± 0.2, and 0.64 ± 0.2, respectively, and the difference between the preoperative and 6-month values was statistically significant (p=0.006). The mean spherical equivalent refraction decreased from -5.6 ± 2.4 diopters (D) preoperatively to -5.0 ± 2.1 D, and mean simulated keratometry decreased from 48.5 ± 2.5 D to 47.8 ± 2.6 D at 6 months. (p=0.145 and p=0.001, respectively). In addition, the maximum keratometry decreased progressively and significantly from the preoperative value during follow-up (p=0.003). The central and minimal corneal thicknesses, including those of the epithelium, also decreased from 442.8 ± 25.6 µm and 430.5 ± 23.9 µm preoperatively to 420.7 ± 31.8 µm and 409.3 ± 28.7 µm at the most recent follow-up (p |
| Databáze: | OpenAIRE |
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