Hemodynamic response of the left gastric vein to glucagon in patients with portal hypertension and esophageal varices
| Autor: | Shoichi Matsutani, Takeshi Fukuzawa, Hitoshi Maruyama, Goro Sato, Hideaki Mizumoto, Hiromitsu Saisho |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Acoustics and Ultrasonics Left gastric vein Vasodilator Agents Biophysics Hemodynamics Collateral Circulation Blood Pressure urologic and male genital diseases Esophageal and Gastric Varices Statistics Nonparametric Veins Esophageal varices Internal medicine Hypertension Portal medicine Humans Radiology Nuclear Medicine and imaging Esophagus Aged Radiological and Ultrasound Technology business.industry Portal Vein Stomach Ultrasonography Doppler Middle Aged medicine.disease Collateral circulation Glucagon female genital diseases and pregnancy complications medicine.anatomical_structure Logistic Models Cardiology Portal hypertension Female Radiology Left gastroepiploic vein business Varices Blood Flow Velocity |
| Zdroj: | Ultrasound in medicinebiology. 29(1) |
| ISSN: | 0301-5629 |
| Popis: | Flow direction and flow velocity of the left gastric vein (LGV) and the portal vein (PV) were examined by a Doppler sonographic machine in 33 patients with esophageal varices, before and after venous injection of glucagon (1 mg). In two patients with hepatopetal blood flow in the LGV, the flow direction changed to hepatofugal after injection of glucagon. In 31 patients with hepatofugal blood flow in the LGV, a significant increase of flow velocity was observed in the LGV in 18 patients (58.1%) and the changes (26.4 +/- 24.6%) were significantly larger than those in the PV (7.9 +/- 16.0%). The changes in flow velocity decreased in the LGV as the diameter of the LGV and the size of varices increased. In conclusion, glucagon increased collateral blood flow in the LGV in portal hypertension. However, the grade of the response decreased as the grade of portal hypertension increased. |
| Databáze: | OpenAIRE |
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