Diabetes mellitus suppresseshemodialysis-induced increases in tear fluid secretion
| Autor: | Takashi Shigematsu, Peter S. Reinach, Yuka Okada, Shizuya Saika, Motoko Nakata, Katsuo Tomoyose, Hirotsugu Kobata |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Dry Eye Syndromes Lacrimal apparatus Autonomic Nervous System Gastroenterology General Biochemistry Genetics and Molecular Biology Diabetes mellitus Diabetic Neuropathies Renal Dialysis Internal medicine medicine Humans Tear secretion Diabetic Nephropathies Uremia Medicine(all) Biochemistry Genetics and Molecular Biology(all) business.industry Incidence Lacrimal Apparatus General Medicine Middle Aged medicine.disease eye diseases Endocrinology medicine.anatomical_structure Tear Basal (medicine) Hemodialysis Tears Female sense organs business Secretory Rate Research Article |
| Zdroj: | BMC Research Notes |
| ISSN: | 1756-0500 |
| Popis: | Background Hemodialysis is essential for the survival of patients suffering from chronic renal failure. However, in diabetics the incidence of dry eye disease is higher than in non-diabetic individuals. Accordingly, we evaluated if this difference is attributable to different effects of hemodialysis on basal tear fluid secretion. Methods A modified Schirmer´s eye test determined if hemodialysis improved basal tear secretion rates in 36 diabetic and non-diabetic patients undergoing hemodialysis. Results Basal tear secretion was invariant in diabetic patients whereas in non-diabetic individuals this process increased. Conclusion In non-diabetic patients, autonomic neuropathy appears to be less severe and somewhat reversible since only in these individuals hemodialysis improved basal tear fluid secretion. This difference may be a factor contributing to the lower incidence of dry eye disease in non-diabetic patients. |
| Databáze: | OpenAIRE |
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