Infants of diabetic mothers
Autor: | Joan L. Nold, Michael K. Georgieff |
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Rok vydání: | 2004 |
Předmět: |
Pediatrics
medicine.medical_specialty Pregnancy in Diabetics Overweight Infant Newborn Diseases Embryonic and Fetal Development Child Development Insulin resistance Pregnancy Diabetes mellitus medicine Hyperinsulinemia Humans business.industry Infant Newborn Infant Prenatal Care medicine.disease Obesity Gestational diabetes Diabetes Gestational Fetal Diseases Fertilization Pediatrics Perinatology and Child Health Female medicine.symptom Metabolic syndrome business |
Zdroj: | Pediatric Clinics of North America. 51:619-637 |
ISSN: | 0031-3955 |
DOI: | 10.1016/j.pcl.2004.01.003 |
Popis: | Advances in the management of the mother with diabetes have reduced the rate of morbidity and mortality for her infant. Aggressive control of maternal glycemic status is warranted, because most morbidities are epidemiologically and pathophysiologically closely linked to fetal hyperglycemia and hyperinsulinemia. The burgeoning public health problem of overweight and obesity in children will likely result in an increased incidence of metabolic syndrome X, characterized by insulin resistance and type II diabetes in adulthood. An early manifestation of this may be glucose intolerance during pregnancy in overweight women without diabetes. Clinicians must continue to have a high degree of suspicion for the diagnosis of diabetes during gestation and screen offspring of women with gestational diabetes for neonatal sequelae. |
Databáze: | OpenAIRE |
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