Risk factors and outcomes for recurrent paediatric in-hospital cardiac arrest: Retrospective multicenter cohort study
| Autor: | Kaitlin Jones, Heather Griffis, Tensing Maa, Javier J. Lasa, Vinay M. Nadkarni, Richard Hanna, Aaron Donoghue, Dana Niles, Robert M. Sutton, Sandeep Gangadharan, Tara L. Petersen, Anita Sen, Takanari Ikeyama, Elizabeth Masse, Diane Atkins, Lynda Knight, Ken Tegtmeyer, Wendy L Van Ittersum, Corinne M. P. Buysse, Kamal Abulebda, Michael R. Flaherty, Jonathan Gilleland, Matthew S. Braga, Andrea Xin Hui Yeo, Jesse Wenger, Stephanie R. Brown, Jennifer Hayes, Orsola Gawronski, Gabry de Jong, Corrado Cecchetti, Joan Roberts, Michael T. Meyer, Heather Wolfe, Stuart Friess, Helen Harvey, Lindsay Ryerson, Alexis A. Topjian, Pricilla Yu, Gene Ong, Priti Jani, Yee Hui Mok, Kelly Corbett, Tia T Raymond, Marc D. Berg, Tara Lemoine, Maria E. Frazier, Dori-Ann Martin, Dana E. Niles, Robert A. Berg, Marcy N. Singleton, Sholeen Nett, Andrea Christoff, Shilpa Balikai, Ryan W. Morgan, Maya Dewan, Kasper G Lauridsen, Denise Welsby, Betsy Hunt, Ichiro Watanabe, Ilana Harwayne-Gidansky, Felice Su, Allan DeCaen, Sophie Skellet, Prakad Rajapreyar, Hiroshi Kurosawa, Jordan Duval-Arnould, Todd Sweberg, Amanda O’Halloran, Daniel Stromberg, Sarah Haskell, Michelle Olson, Javier Urbano Villaescusa, Luz Marina Mejia, Adam Cheng, Jimena del Castillo, Monica E. Kleinman, Ivie Esangbedo, Kiran Heber, Oscar Tegg, Utpal Bhalala |
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| Přispěvatelé: | Pediatric Surgery |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent medicine.medical_treatment Emergency Nursing Cohort Studies Continuous variable Risk Factors Interquartile range Internal medicine Chi-square test Humans Medicine Cardiopulmonary resuscitation Child Retrospective Studies business.industry Retrospective cohort study Hospitals Pediatric Cardiopulmonary Resuscitation Heart Arrest Cohort Propensity score matching Emergency Medicine Cardiology and Cardiovascular Medicine business Cohort study |
| Zdroj: | Resuscitation, 169, 60-66. Elsevier Ireland Ltd |
| ISSN: | 0300-9572 |
| Popis: | Aim of study: Recurrent in-hospital cardiac arrest (IHCA) is associated with morbidity and mortality in adults. We aimed to describe the risk factors and outcomes for paediatric recurrent IHCA. Methods: Retrospective cohort study of patients ≤18 years old with single or recurrent IHCA. Recurrent IHCA was defined as ≥2 IHCA within the same hospitalization. Categorical variables expressed as percentages and compared via Chi square test. Continuous variables expressed as medians with interquartile ranges and compared via rank sum test. Outcomes assessed in a propensity match cohort. Results: From July 1, 2015 to January 26, 2021, 139/894 (15.5%) patients experienced recurrent IHCA. Compared to patients with a single IHCA, recurrent IHCA patients were more likely to be trauma and less likely to be surgical cardiac patients. Median duration of cardiopulmonary resuscitation (CPR) was shorter in the recurrent IHCA (5 vs. 11 min; p < 0.001) with no difference in IHCA location or immediate cause of CPR. Patients with recurrent IHCA had worse survival to intensive care unit (ICU) discharge (31% vs. 52%; p < 0.001), and worse survival to hospital discharge (30% vs. 48%; p < 0.001) in unadjusted analyses and after propensity matching, patients with recurrent IHCA still had worse survival to ICU (34% vs. 67%; p < 0.001) and hospital (31% vs. 64%; p < 0.001) discharge. Conclusion: When examining those with a single vs. a recurrent IHCA, event and patient factors including more pre-existing conditions and shorter duration of CPR were associated with risk for recurrent IHCA. Recurrent IHCA is associated with worse survival outcomes following propensity matching. |
| Databáze: | OpenAIRE |
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