Pharmacologic therapeutic window of pramiracetam demonstrated in behavior, EEG, and single neuron firing rates

Autor:	F. W. Ninteman, B. P. H. Poschel, M. J. Callahan, P. M. Ho
Rok vydání:	1985
Předmět:	Male Pyrrolidines Physostigmine Administration Oral Electroencephalography Hippocampal formation Nootropic Cellular and Molecular Neuroscience Oral administration medicine Animals Learning Molecular Biology Neurons Pharmacology Behavior Animal medicine.diagnostic_test business.industry Pramiracetam Piracetam Cognition Cell Biology Rats Inbred F344 Rats Electrophysiology medicine.anatomical_structure nervous system Anesthesia Injections Intravenous Molecular Medicine Neuron business Neuroscience medicine.drug
Zdroj:	Experientia. 41:1153-1156
ISSN:	1420-9071 0014-4754
DOI:	10.1007/bf01951704
Popis:	Following oral or intravenous administration, a representative cognition activator drug, pramiracetam sulfate, is shown to have a pharmacologic therapeutic window at three different levels of study: learned behavior, gross EEG activity of the frontal cortex and hippocampus, and firing rate of single hippocampal neurons.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dcf1f46befcf199df6b4a54343d117 https://doi.org/10.1007/bf01951704 Zobrazit plný text záznamu Full text from SpringerLink