Prediction of neonates' macrosomia with maternal lipid profile of healthy mothers
| Autor: | Elaheh Mossayebi, Mojgan Rahmaniyan, Zohreh Arab, Ali Kabir, Fariba Almassinokiani |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Birth weight normal pregnancy Gestational Age large for gestational age Fetal Macrosomia Pregnancy Fetal macrosomia Medicine Birth Weight Humans Pediatrics Perinatology and Child Health Fetus medicine.diagnostic_test business.industry Obstetrics lcsh:RJ1-570 Infant Newborn lcsh:Pediatrics medicine.disease Obesity Lipids gestational diabetes mellitus Gestational diabetes lipid profile Logistic Models Pediatrics Perinatology and Child Health Female business Lipid profile Cohort study |
| Zdroj: | Pediatrics and Neonatology, Vol 55, Iss 1, Pp 28-34 (2014) |
| ISSN: | 2212-1692 |
| Popis: | BackgroundThe aim of this study is to identify the association between the lipid profile of healthy nondiabetic, nonobese pregnant women in the first weeks of the third trimester of pregnancy and macrosomia or large-for-gestational-age (LGA) neonates with normal pregnancies.Materials and methodsIn this cohort study, 200 pregnant healthy women without gestational diabetes mellitus (GDM), obesity, or hypertension and carrying a single fetus in a prenatal clinic of a referral hospital were included based on a convenience sampling. Then, we took a blood sample to assess fasting blood sugar (FBS), triglyceride (TG), total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL). GDM was assessed after administering 50 g of oral glucose. All cases were followed until the end of pregnancy. The main outcome measurement was neonatal birth weight.ResultsOnly 154 mothers met eligibility criteria. There were eight cases (5.2%) with macrosomia (birth weight ≥ 4000 g) and 35 cases (22.7%) with LGA. Linear regression showed that mothers’ TG and neonates’ gender were independent predictors of the birth weight of the children (R-square = 0.52, p 4500 g), but also for LGA. |
| Databáze: | OpenAIRE |
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