Resistant Starch Consumption Effects on Glycemic Control and Glycemic Variability in Patients with Type 2 Diabetes: A Randomized Crossover Study
| Autor: | Yolanda Arias-Córdova, Carlos Alfonso Tovilla-Zárate, Viridiana Olvera-Hernández, José D. Méndez, Meztli Ramos-García, Isela Esther Juárez-Rojop, Jorge L. Ble-Castillo, Adrián Navarrete-Cortes, Carlos García-Vázquez, Mirian Carolina Martínez-López, Guadalupe Jiménez-Domínguez |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Blood Glucose Male resistant starch food.ingredient Starch Type 2 diabetes Glycemic Control Zea mays Maize starch Article chemistry.chemical_compound Animal science food medicine Humans TX341-641 In patient Obesity Resistant starch Glycemic Nutrition and Dietetics Cross-Over Studies Nutrition. Foods and food supply Continuous glucose monitoring business.industry Blood Glucose Self-Monitoring food and beverages Middle Aged medicine.disease Crossover study banana chemistry Diabetes Mellitus Type 2 embryonic structures glycemic variability Female continuous glucose monitoring Amylose type 2 diabetes business Food Science |
| Zdroj: | Nutrients Volume 13 Issue 11 Nutrients, Vol 13, Iss 4052, p 4052 (2021) |
| ISSN: | 2072-6643 |
| Popis: | We previously observed beneficial effects of native banana starch (NBS) with a high resistant starch (RS) content on glycemic response in lean and obese participants. Here, we aimed to determine the effects of NBS and high-amylose maize starch (HMS) on glycemic control (GC) and glycemic variability (GV) in patients with type 2 diabetes (T2D) when treatments were matched for digestible starch content. In a randomized, crossover study, continuous glucose monitoring (CGM) was performed in 17 participants (aged 28–65 years, BMI ≥ 25 kg/m2, both genders) consuming HMS, NBS, or digestible maize starch (DMS) for 4 days. HMS and NBS induced an increase in 24 h mean blood glucose during days 2 to 4 (p < 0.05). CONGA, GRADE, and J-index values were higher in HMS compared with DMS only at day 4 (p < 0.05). Yet, NBS intake provoked a reduction in fasting glycemia changes from baseline compared with DMS (p = 0.0074). In conclusion, under the experimental conditions, RS from two sources did not improve GC or GV. Future longer studies are needed to determine whether these findings were affected by a different baseline microbiota or other environmental factors. |
| Databáze: | OpenAIRE |
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