Gastric pouch emptying of solid food in patients with successful and unsuccessful weight loss after Roux-en-Y gastric bypass surgery
| Autor: | Ignace M. C. Janssen, Laura N. Deden, M. I. Cooiman, Frits J. Berends, Martin Gotthardt, Edo O. Aarts, Baudewijn W. Hendrickx |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Gastric Bypass 030209 endocrinology & metabolism medicine.disease_cause Gastroenterology Body Mass Index 03 medical and health sciences All institutes and research themes of the Radboud University Medical Center 0302 clinical medicine Weight loss Internal medicine Weight Loss Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14] medicine Ingestion Humans Postoperative Period Radionuclide Imaging Retrospective Studies Meal Gastric emptying business.industry Gastric bypass surgery Middle Aged Roux-en-Y anastomosis Obesity Morbid Gastric Emptying 030211 gastroenterology & hepatology Surgery Female Laparoscopy Pouch medicine.symptom business Body mass index Follow-Up Studies |
| Zdroj: | Surgery for Obesity and Related Diseases, 13, 1840-1846 Surgery for Obesity and Related Diseases, 13, 11, pp. 1840-1846 |
| ISSN: | 1550-7289 |
| DOI: | 10.1016/j.soard.2017.07.031 |
| Popis: | Background After Roux-en-Y gastric bypass (RYGB), approximately 10% of patients have insufficient weight loss (excess body mass index loss Objectives To compare pouch emptying of patients with poor weight loss and patients with successful weight loss after RYGB. Setting A research-intensive nonacademic hospital and center of expertise in bariatric surgery in the Netherlands Methods Female patients were included from among patients with the least (poor weight loss group [P-WL]) and the most weight loss (successful weight loss group [S-WL]) in our center 2 years after RYGB. Pouch emptying scintigraphy was performed after ingestion of a radiolabeled solid meal. Emptying curves, intestinal content (IC) at meal completion and after 15, 30, 45, and 60 minutes, half emptying time, and maximal pouch emptying rate were compared. Results Five individuals were included in P-WL and 5 in S-WL, on average 2.5 ± .3 years after RYGB. Total weight loss was 18 ± 4.1% in P-WL and 44 ± 5.7% in S-WL (P In P-WL, a fast initial pouch emptying and exponential emptying curve was observed, compared with a slower initial emptying and more linear curve in S-WL. Faster emptying in P-WL was also shown by a larger ICmeal (42 ± 18% versus 4.0 ± 3.3%,), IC15 (76 ± 15% versus 35 ± 22%), and IC30 (85 ± 12% versus 54 ± 25%), and a greater maximal pouch emptying rate (17 ± 4.7 versus 5.6 ± 3.4%/min) compared with S-WL (P Conclusions Pouch emptying for solid food was faster in patients with the least weight loss compared with patients with the most weight loss after RYGB. If pouch emptying is an important mechanism in weight loss, altering the pouch outlet may improve poor weight loss management. |
| Databáze: | OpenAIRE |
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