Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells

Autor: Lioudmila V. Sharova, Yulan Piao, Alexei A. Sharov, Nabeebi Shaik, Minoru S.H. Ko, Timur Nedorezov
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
ISSN: 1756-1663
1340-2838
Popis: Degradation of mRNA is one of the key processes that control the steady-state level of gene expression. However, the rate of mRNA decay for the majority of genes is not known. We successfully obtained the rate of mRNA decay for 19 977 non-redundant genes by microarray analysis of RNA samples obtained from mouse embryonic stem (ES) cells. Median estimated half-life was 7.1 h and only
Databáze: OpenAIRE