New Perspectives on the Evolution of Within-Individual Genome Variation and Germline/Soma Distinction
| Autor: | Anne-Marie Dion-Côté, Alexander Suh |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
AcademicSubjects/SCI01140
Biology Genome within-Individual Genome Variation and Germline/Soma Distinction Germline germline/soma variation Genome variation 03 medical and health sciences 0302 clinical medicine Germline mutation germline-restricted chromosome Genetics medicine Ecology Evolution Behavior and Systematics 030304 developmental biology 0303 health sciences AcademicSubjects/SCI01130 DNA elimination medicine.anatomical_structure Evolutionary biology Genome Biology chromatin diminution Soma Programmed DNA elimination Ploidy 030217 neurology & neurosurgery Perspectives |
| Zdroj: | Genome Biology and Evolution |
| ISSN: | 1759-6653 |
| Popis: | Genomes can vary significantly even within the same individual. The underlying mechanisms are manifold, ranging from somatic mutation and recombination, development-associated ploidy changes and genetic bottlenecks, over to programmed DNA elimination during germline/soma differentiation. In this perspective piece, we briefly review recent developments in the study of within-individual genome variation in eukaryotes and prokaryotes. We highlight a Society for Molecular Biology and Evolution 2020 virtual symposium entitled “Within-individual genome variation and germline/soma distinction” and the present Special Section of the same name in Genome Biology and Evolution, together fostering cross-taxon synergies in the field to identify and tackle key open questions in the understanding of within-individual genome variation. |
| Databáze: | OpenAIRE |
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