Immature Teratoma of the Ovary with a Minor Rhabdomyosarcomatous Component and Fatal Rhabdomyosarcomatous Metastases: The First Case in a Child
| Autor: | Tadashi Yoshino, Yoko Tabuchi, Hiroyuki Yanai, Hiroo Matsuura, Yoshiteru Takada, Masahiro Kawasaki |
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| Rok vydání: | 2002 |
| Předmět: |
Pathology
medicine.medical_specialty endocrine system diseases Ovariectomy Ovary Ovarian Rhabdomyosarcoma Pathology and Forensic Medicine Fatal Outcome Antineoplastic Combined Chemotherapy Protocols Rhabdomyosarcoma medicine Humans Child Pelvic Neoplasms Ovarian Neoplasms business.industry Teratoma Obstetrics and Gynecology medicine.disease Primary tumor female genital diseases and pregnancy complications medicine.anatomical_structure Dermoid cyst Female Immature teratoma Sarcoma Neoplasm Recurrence Local business |
| Zdroj: | International Journal of Gynecological Pathology. 21:82-85 |
| ISSN: | 0277-1691 |
| Popis: | A case of ovarian immature teratoma with rhabdomyosarcomatous recurrence in a 6-year-old girl is described. The primary tumor consisted of a dermoid cyst and a solid nodule composed of mature and immature mesenchymal tissue. The most immature mesenchymal cells showed no distinctive differentiation except for focal rhabdomyoblastic differentiation. The primary tumor was diagnosed as immature teratoma, grade 2, stage IIa. Despite left oophorectomy and excision of uterine serosal implants, chemotherapy, and radiation, four intrapelvic recurrences developed within 3 years. Although the primary tumor contained only a few rhabdomyoblasts, the recurrent tumors became increasingly rhabdomyosarcomatous. The patient died of systemic disease 3 years after presentation. This case and previous reports indicate that the prognosis of patients with ovarian immature teratoma with rhabdomyosarcomatous recurrence is poor and similar to that of primary ovarian rhabdomyosarcoma. |
| Databáze: | OpenAIRE |
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