Challenges In Early Glaucoma Detection

Autor: Suzana Pavljasevic, Almir Dervisevic, Sanja Sefic Kasumovic, Edita Dervisevic
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Adult
Male
Retinal Ganglion Cells
medicine.medical_specialty
genetic structures
Optic Disk
Optic disk
Glaucoma
02 engineering and technology
Retinal ganglion
Optic neuropathy
03 medical and health sciences
Young Adult
0302 clinical medicine
Atrophy
Risk Factors
Ophthalmology
0202 electrical engineering
electronic engineering
information engineering

medicine
Myopia
Humans
Prospective Studies
early detection
Aged
Retrospective Studies
Original Paper
business.industry
General Medicine
Middle Aged
medicine.disease
eye diseases
Visual field
optic neuropathy
Observational Studies as Topic
medicine.anatomical_structure
Early Diagnosis
030221 ophthalmology & optometry
Optic nerve
020201 artificial intelligence & image processing
Female
sense organs
Visual Fields
business
Tomography
Optical Coherence

Optic disc
Zdroj: Medical Archives
ISSN: 1986-5961
0350-199X
Popis: Introduction Glaucoma is the most common optic neuropathy which is characterized by progressive loss of retinal ganglion cells, the excavation of the optic nerve head, associated with defects in the visual field. It is not a disease, but the final result of united and yet completely unidentified cellular and subcellular processes and effects of many factors responsible for changes in retinal ganglion cells leading to their accelerated apoptosis. Methods This is a prospective-retrospective, comparative, randomized clinical trial that included 150 patients, 97 were female and 53 male. The age of patients ranged from 18 to 80 years. Results The highest degree of myopia in category of tilted optic discs had patients with large disc (4.05 + -0.65). Values of the degree of myopia have linearly declined in relation to the size of the oblique disc. The analysis of the results revealed that the subjects who had a higher degree of myopia associated with glaucoma had frequent parapapillar atrophy of alpha and beta zones. The highest percentage of subjects with parapapillar changes were in the group of patients who had other than glaucoma and myopia (62%), then in the group of patients with glaucoma only (56%). Conclusion Previous studies on the relationship between myopia and open-angle glaucoma are based on the results of observational studies. However, according to recent findings, based on the available studies, the systematic approach to estimate the association between myopia and glaucoma does not exist. Disc Damage Likelihood Scale (DDLS) is a new system for assessing glaucomatous damage of the optic disc which strongly correlates with the degree of visual field loss.
Databáze: OpenAIRE