Most antidepressant use in primary care is justified; results of the Netherlands Study of Depression and Anxiety
| Autor: | Klaas van der Meer, Ellen Piek, Witte J.G. Hoogendijk, Brenda W.J.H. Penninx, Willem A. Nolen |
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| Přispěvatelé: | EMGO+ - Mental Health, Science in Healthy Ageing & healthcaRE (SHARE), Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Life Course Epidemiology (LCE), Psychiatry, EMGO - Mental health |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
DISORDER medicine.medical_specialty Adolescent FEASIBILITY APPROPRIATENESS Population lcsh:Medicine Primary care Anxiety GUIDELINES Secondary care Young Adult Pharmacotherapy SDG 3 - Good Health and Well-being GENERAL-PRACTICE Medicine Humans Young adult DIAGNOSTIC INTERVIEW CIDI Psychiatry education lcsh:Science Depression (differential diagnoses) POPULATION Aged Netherlands education.field_of_study Multidisciplinary Primary Health Care business.industry Depression Mental Health/Mood Disorders lcsh:R RECOGNITION Middle Aged Antidepressive Agents Mental Health RELIABILITY Antidepressant Mental Health/Psychopharmacology lcsh:Q medicine.symptom business FOLLOW-UP Research Article |
| Zdroj: | Piek, E, van der Meer, K, Hoogendijk, W J G, Penninx, B W J H & Nolen, W A 2011, ' Most antidepressant use in primary care is justified; results of the Netherlands Study of Depression and Anxiety ', PLoS ONE, vol. 6, no. 3, e14784 . https://doi.org/10.1371/journal.pone.0014784 PLoS ONE PLoS ONE, 6(3):e14784. Public Library of Science PLoS ONE, 6(3):14784. PUBLIC LIBRARY SCIENCE PLoS ONE, Vol 6, Iss 3, p e14784 (2011) PLoS ONE, 6(3) |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0014784 |
| Popis: | Background: Depression is a common illness, often treated in primary care. Many studies have reported undertreatment with antidepressants in primary care. Recently, some studies also reported overtreatment with antidepressants. The present study was designed to assess whether treatment with antidepressants in primary care is in accordance with current guidelines, with a special focus on overtreatment.Methodology: We used baseline data of primary care respondents from the Netherlands Study of Depression and Anxiety (NESDA) (n = 1610). Seventy-nine patients with treatment in secondary care were excluded. We assessed justification for treatment with antidepressant according to the Dutch primary care guidelines for depression and for anxiety disorders. Use of antidepressants was based on drug-container inspection or, if unavailable, on self-report. Results were recalculated to the original population of primary care patients from which the participants in NESDA were selected (n = 10,677).Principal Findings: Of 1531 included primary care patients, 199 (13%) used an antidepressant, of whom 188 (94.5%) (possibly) justified. After recalculating these numbers to the original population (n = 10,677), we found 908 (95% CI 823 to 994) antidepressant users. Forty-nine (95% CI 20 to 78) of them (5.4%) had no current justification for an antidepressant, but 27 of them (54.5%) had a justified reason for an antidepressant at some earlier point in their life.Conclusions: We found that overtreatment with antidepressants in primary care is not a frequent problem. Too long continuation of treatment seems to explain the largest proportion of overtreatment as opposed to inappropriate initiation of treatment. |
| Databáze: | OpenAIRE |
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