Update on blood pressure control and renal outcomes in diabetes mellitus
| Autor: | Robert J. Anderson, Mark Henry Joven |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism medicine.medical_treatment Blood Pressure Disease Diabetic nephropathy Renin-Angiotensin System Internal medicine Diabetes mellitus Internal Medicine medicine Humans Diabetic Nephropathies Renal replacement therapy Intensive care medicine business.industry Type 2 Diabetes Mellitus medicine.disease Blood pressure Hypertension Practice Guidelines as Topic Albuminuria Disease Progression medicine.symptom business Kidney disease |
| Zdroj: | Current diabetes reports. 15(7) |
| ISSN: | 1539-0829 |
| Popis: | Diabetic nephropathy (DN) is associated with a high incidence of cardiovascular (CV) morbidity and mortality. Although relationships between hypertension and diabetic nephropathy are complex, blood pressure (BP) control is an important management strategy in the prevention of onset and progression of DN in patients with diabetes mellitus (DM). Recent guidelines recommend less stringent BP targets among patients with type 2 DM and chronic kidney disease. These recommendations are based mostly on lack of benefit in CV outcomes with a low BP target. We review the current information on efficacy of BP control in improving renal outcomes in patients with type 2 DM. Presently, although intensive BP control has been was beneficial in decreasing albuminuria, it has not translated into reductions in risks of hard renal endpoints, such as progression to end-stage renal disease, the need for renal replacement therapy, and mortality from renal causes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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