Possibilities of using natural mineral waters in the treatment of patients with non-alcoholic fatty liver disease

Autor: Natalia Вadiuk, Khrystyna Koieva, Natalia Dragomiretska, Anna Izha, Sergey Gushcha, B. A. Nasibullin, Iryna Zabolotna
Rok vydání: 2019
Předmět:
Zdroj: Balneo Research Journal, Vol 10, Iss 4, Pp 450-456 (2019)
ISSN: 2069-7619
2069-7597
Popis: GUSHCHA Sergey, DRAGOMIRETSKA Natalia, ZABOLOTNA Iryna, NASIBULLIN Boris, IZHA Anna, ВADIUK Natalia, KOIEVA Khrystyna. Possibilities of using natural mineral waters in the treatment of patients with non-alcoholic fatty liver disease. Balneo Research Journal. Vol.10, No.4, December 2019 p: 450–456. DOI: http://dx.doi.org/10.12680/balneo.2019.280 https://zenodo.org/record/4012200 Possibilities of using natural mineral waters in the treatment of patients with non-alcoholic fatty liver disease GUSHCHA Sergey1, DRAGOMIRETSKA Natalia1, ZABOLOTNA Iryna1, NASIBULLIN Boris1, IZHA Anna1, ВADIUK Natalia2, KOIEVA Khrystyna1 1State Institution «Ukrainian Scientific-Research Institute of Medical Rehabilitation and Balneology, the Ministry of Public Health of Ukraine», Odessa 2State Enterprise Ukrainian Research Institute for Medicine of Transport, the Ministry of Public Health of Ukraine», Odessa Non-alcoholic fatty liver disease (NAFLD) is a chronic pathology that is increasingly diagnosed in different countries. The pathogenesis of NAFLD associated with insulin resistance, abdominal obesity, atherogenic dyslipidemia, arterial hypertension, endothelial dysfunction, impaired adipokine secretion, that is, components of metabolic syndrome. Treatment of NAFLD should be comprehensive and lengthy, although there are no standardized approaches to the treatment of NAFLD. Meanwhile, drug therapy carries certain risks: the development of serious adverse reactions with prolonged use. The work highlights modern views on the etiology, epidemiology, pathogenesis, drug and non-drug treatment of non-alcoholic fatty liver disease (NAFLD). Experimental and clinical studies on the mechanism of biological action, the effects of using different in composition and mineralization of mineral waters on the course of NAFLD had presented. Based on experimental and clinical studies, ideas about the specificity of the action of mineral waters of various balneological types and mineralization on the clinical course of NAFLD at different stages of the disease, the effect on the functional state of the liver, and the dynamics of lipid and carbohydrate metabolism had detailed. It is concluded that mineral waters could be successfully used in the complex treatment of NAFLD patients. Key words: non-alcoholic fatty liver disease; insulin resistance; dyslipidemia; mineral waters
Databáze: OpenAIRE