Predicting the Fibroid-Migratory Impact of UAE: Role of Pre-embolization MRI Characteristics
| Autor: | Leto Mailli, Salvatore Alessio Angileri, Joo-Young Chun, Eric Y Auyoung, Anna-Maria Belli, Lakshmi Ratnam, Sourav Das, Seyed Ameli-Renani, Isaac Manyonda, Raj Das |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Shortest distance Fibroids Uterine fibroids medicine.medical_treatment Uterine artery embolisation Infarction Uterine fibroid embolisation Gynaecologic interventions 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Paired samples medicine Humans Radiology Nuclear Medicine and imaging Embolization Clinical Investigation Fibroid MRI Retrospective Studies Leiomyoma business.industry Ultrasound Uterus Middle Aged Uterine Artery Embolization medicine.disease Mr imaging Magnetic Resonance Imaging female genital diseases and pregnancy complications Endometrial cavity Treatment Outcome 030220 oncology & carcinogenesis Uterine Neoplasms Female Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cardiovascular and Interventional Radiology |
| ISSN: | 1432-086X 0174-1551 |
| Popis: | Aim To investigate potential factors on MR imaging that could be used to predict migration of uterine fibroids post-UAE. Methods and Materials We retrospectively reviewed patients referred for UAE having pre-procedural and 6 months post-procedural MRI, at a tertiary centre, over a 1-year period. Pre- and post-UAE images were reviewed in 64 women by two radiologists to identify the sub-type, dimensions, and infarction rate of each dominant fibroid. The shortest distance between the fibroid and the endometrial wall was measured to determine intramural fibroid movement. Paired sample T tests and two-sample T tests were used to compare between pre- and post-embolization variations and between migrated and non-migrated intramural fibroids, respectively. After preliminary results suggested potential predictors of intramural fibroids migration, we tested our findings against the non-dominant intramural fibroids in the same patients. Results Review of images revealed 35 dominant intramural fibroids, of which eight migrated to become submucosal fibroids, while five were either partially or completely expelled. These 13 migrated fibroids had a shorter pre-procedural minimum endometrial distance (range 1–2.4 mm) and greater maximum fibroid diameter (range 5.1–18.1 cm), when compared to non-migrating fibroids. On image reassessment, the migrated non-dominant intramural fibroids had a minimum endometrial distance and maximum fibroid diameter within the same range. Conclusion Intramural fibroids with a minimum endometrial distance less than 2.4 mm and a maximum fibroid diameter greater than 5.1 cm have a high likelihood of migrating towards the endometrial cavity after UAE. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink