Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from 'Guatambú' trees (Aspidosperma australe and Balfourodendron riedelianum)
| Autor: | Cristian Manuel Pis Diez, Miriam Cristina Perez, MARíA Belén Valdez, Mónica García, Analia Paola, Esteban Avigliano, Jorge Alejandro Palermo, Guillermo Blustein |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Aspidosperma
N-methyltetrahydroellipticine Biofouling Ingeniería Forestal Bioengineering Flindersiamine Olivacine 01 natural sciences Biochemistry Balfourodendron riedelianum KOKUSAGININE purl.org/becyt/ford/1 [https] FLINDERSIAMINE Botany purl.org/becyt/ford/1.4 [https] Animals Rutaceae Molecular Biology N-METHYLTETRAHYDROELLIPTICINE Indole test biology 010405 organic chemistry Chemistry Aspidosperma australe Biological activity General Chemistry General Medicine Química Antifouling biology.organism_classification Mytilus Bivalvia 0104 chemical sciences Indole alkaloids ANTIFOULING 010404 medicinal & biomolecular chemistry Kokusaginine Quinolines BIOLOGICAL ACTIVITY Molecular Medicine INDOLE ALKALOIDS Brazil |
| Zdroj: | CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET |
| Popis: | In this work, the antifouling activity of five alkaloids, isolated from trees of the Atlantic rainforest, was studied. The tested alkaloids were olivacine (1), uleine (2) and N-methyltetrahydroellipticine (3) from Aspidosperma australe ('yellow guatambu') and the furoquinoline alkaloids kokusaginine (4) and flindersiamine (5) from Balfourodendron riedelianum ('white guatambu'). All these compounds can be isolated from their natural sources in high yields in a sustainable way. The five compounds were subjected to laboratory tests (attachment test of the mussel Mytilus edulis platensis) and field trials, by incorporation into soluble matrix paints, and 45 days of exposure of the painted panels in the sea. The results show that compound 3 is a very potent antifoulant, and that compounds 4 and 5 are also very active, while compounds 1 and 2 did not show any significant antifouling activity. These results open the way for the development of environmentally friendly antifouling agents, based on abundant and easy-to-purify compounds that can be obtained in a sustainable way. Centro de Investigación y Desarrollo en Tecnología de Pinturas Facultad de Ciencias Naturales y Museo |
| Databáze: | OpenAIRE |
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