Growth and nutritional status in children and adolescents with cystic fibrosis

Autor:	Charles Susanne, Wioleta Umławska
Rok vydání:	2008
Předmět:	Aging Pediatrics Cystic Fibrosis Physiology Epidemiology Cystic Fibrosis Transmembrane Conductance Regulator Cystic fibrosis Body Mass Index Cohort Studies Reference Values Medicine Child Growth Disorders education.field_of_study Body proportions Anthropometry biology Age Factors Nutritional status Reference Standards Thorax Cystic fibrosis transmembrane conductance regulator Child Preschool Analysis of variance medicine.symptom Delayed puberty medicine.medical_specialty Adolescent Population Neonatal Screening Internal medicine Genetics Humans education Analysis of Variance business.industry Body Weight Malnutrition Puberty Infant Newborn Public Health Environmental and Occupational Health Infant medicine.disease Body Height Endocrinology Mutation biology.protein Poland business
Zdroj:	Annals of Human Biology. 35:145-153
ISSN:	1464-5033 0301-4460
Popis:	Growth retardation, delayed puberty and malnutrition are frequently observed in children suffering from cystic fibrosis.The aim of this study was to estimate growth and nutritional status in children with cystic fibrosis on the basis of body proportions and body mass index.Anthropometric data were collected from the medical histories of 62 patients treated in three cystic fibrosis treatment centers in Poland. Anthropometric parameters were expressed in terms of standard deviations away from age-specific and sex-specific reference means reported for the population of Poland. Two-way analysis of variance was used to determine whether the type of cystic fibrosis transmembrane conductance regulator (CFTR) mutation is correlated with age at the time of diagnosis and with body proportions.The type of mutation was significantly correlated with height, weight and transverse chest width. Growth retardation was greater in subjects diagnosed before they were 3 years old than in subjects diagnosed later. The children had infantile body proportions. Their legs were short and their trunks were long in comparison to their height. Almost 40% of the subjects suffered from malnourishment.Further study is needed to determine how growth in children with cystic fibrosis is affected by clinical practice and socio-economic factors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a430fd1f238b5e12fb4df64546aded https://doi.org/10.1080/03014460701824132 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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