BIÓPSIA HEPÁTICA PÓS-REPERFUSÃO E SUA UTILIZAÇÃO NA PREDIÇÃO DA MORTALIDADE E DA DISFUNÇÃO HEPÁTICA PÓS-TRANSPLANTE
| Autor: | Larissa Luvison Gomes da Silva, Marcos Vinícius Zanchet, Jorge Eduardo Fouto Matias, Júlio Cezar Uili Coelho |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Pathology Transplante Hepático Complications Hepatic Biopsy Survival Biópsia Hepática Biopsy medicine.medical_treatment RC799-869 Liver transplantation Gastroenterology 0302 clinical medicine medicine.diagnostic_test General Medicine Middle Aged Diseases of the digestive system. Gastroenterology Liver Sobrevida 030220 oncology & carcinogenesis Liver biopsy Predictive value of tests Reperfusão Original Article Female 030211 gastroenterology & hepatology Complicações Adult medicine.medical_specialty Adolescent RD1-811 Primary Graft Dysfunction Context (language use) Liver Transplant Young Adult 03 medical and health sciences Predictive Value of Tests Internal medicine medicine Humans Aged Retrospective Studies business.industry Disfunção Primária do Enxerto medicine.disease Liver Transplantation Transplantation Reperfusion Surgery Steatosis business |
| Zdroj: | ABCD: Arquivos Brasileiros de Cirurgia Digestiva, Vol 29, Iss 3, Pp 189-193 (2016) ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), Volume: 29, Issue: 3, Pages: 189-193, Published: SEP 2016 ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) v.29 n.3 2016 ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) Colégio Brasileiro de Cirurgia Digestiva (CBCD) instacron:CBCD Arquivos Brasileiros de Cirurgia Digestiva : ABCD |
| ISSN: | 0102-6720 |
| Popis: | Background: The outcome of the patients after liver transplant is complex and to characterize the risk for complications is not always easy. In this context, the hepatic post-reperfusion biopsy is capable of portraying alterations of prognostic importance. Aim: To compare the results of liver transplantation, correlating the different histologic features of the hepatic post-reperfusion biopsy with graft dysfunction, primary non-function and patient survival in the first year after transplantation. Method: From the 377 transplants performed from 1996 to 2008, 164 patients were selected. Medical records were reviewed and the following clinical outcomes were registered: mortality in 1, 3, 6 and 12 months, graft dysfunction in varied degrees and primary graft non-function. The post-reperfusion biopsies had been examined by a blinded pathologist for the outcomes. The following histological variables had been evaluated: ischemic alterations, congestion, steatosis, neutrophilic exudate, monomorphonuclear infiltrate and necrosis. Results: The variables associated with increased mortality were: steatosis (p=0.02209), monomorphonuclear infiltrate (p=0.03935) and necrosis (p |
| Databáze: | OpenAIRE |
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