Age-Related Frailty: A Clinical Model for Geroscience?
| Autor: | Sandrine Sourdet, P. de Souto Barreto, F. Sierra, E. Setphan, Davide Angioni, Bruno Vellas, Tony Macaron, C. Takeda |
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| Rok vydání: | 2020 |
| Předmět: |
Gerontology
Aging Frail Elderly media_common.quotation_subject Medicine (miscellaneous) Comorbidity Disease Temptation 03 medical and health sciences 0302 clinical medicine Age related Activities of Daily Living Humans Medicine Medical history 030212 general & internal medicine Aged 030304 developmental biology media_common Quality of Life Research Aged 80 and over 0303 health sciences Nutrition and Dietetics Frailty Geroscience business.industry Geriatrics gerontology Age Factors Multimorbidity medicine.disease Geriatrics and Gerontology business |
| Zdroj: | The journal of nutrition, health & aging. 24:1140-1143 |
| ISSN: | 1760-4788 1279-7707 |
| DOI: | 10.1007/s12603-020-1491-4 |
| Popis: | In their everyday practice, geriatricians are confronted with the fact that older age and multimorbidity are associated to frailty. Indeed, if we take the example of a very old person with no diseases that progressively becomes frail with no other explanation, there is a natural temptation to link frailty to aging. On the other hand, when an old person with a medical history of diabetes, arthritis and congestive heart failure becomes frail there appears an obvious relationship between frailty and comorbidity. The unsolved question is: Considering that frailty is multifactorial and in the majority of cases comorbidity and aging are acting synergistically, can we disentangle the main contributor to the origin of frailty: disease or aging? We believe that it is important to be able to differentiate age-related frailty from frailty related to comorbidity. In fact, with the emergence of geroscience, the physiopathology, diagnosis, prognosis and treatment will probably have to be different in the future. |
| Databáze: | OpenAIRE |
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