Comparison of Clinical and Diagnostic Features of Pediatric Oncology Patients With or Without COVID-19 Infection: A Retrospective Chart Review
| Autor: | Saba Shahid, Neelum Mansoor, Naeem Jabbar, Naila Rafiq, Sidra Maqsood |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Lymphocytosis Coronavirus disease 2019 (COVID-19) Malignancy Severity of Illness Index Fraction of inspired oxygen Chart review Internal medicine Pediatric oncology medicine Humans Child Retrospective Studies Respiratory Distress Syndrome medicine.diagnostic_test SARS-CoV-2 business.industry COVID-19 Complete blood count Retrospective cohort study Hematology medicine.disease Oncology Child Preschool Pediatrics Perinatology and Child Health medicine.symptom business |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 44:e658-e664 |
| ISSN: | 1077-4114 |
| Popis: | There is a scarcity of data summarizing the clinical picture, laboratory, and imaging findings and outcome in children with malignancy and coronavirus disease 2019 (COVID-19) infection. This study characterizes a detailed comparison of pediatric oncology patients with and without COVID infection. A retrospective study was conducted at The Indus Hospital, Karachi, from March 2020 to June 2020. Clinical presentation, laboratory and imaging findings, disease severity, and outcome were compared between cohorts. The mean age of children with and without COVID was 8.0±4.9 and 7.4±4.1 years, respectively. Hematologic malignancy comprised the largest number of patients, followed by solid tumors. Lymphocytosis and low neutrophil-lymphocyte ratio was observed in the COVID positive group. Cardiac dysfunction (1.4% vs. 0%), acute respiratory distress syndrome (8% vs. 0%) and lower peripheral capillary oxygen saturation/fraction of inspired oxygen ratio (473 vs. 486) found to be associated with severe disease in COVID positive group (P |
| Databáze: | OpenAIRE |
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