Fertility management in the PCOS population: results of a web-based survey at IVF-worldwide.com
| Autor: | Virginia Mensah, Yulian Zhao, Adam H. Balen, Paul R. Brezina, Milton Leong, Ariel Weissman, Zeev Shoham |
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| Rok vydání: | 2013 |
| Předmět: |
Infertility
medicine.medical_specialty endocrine system diseases International scale education Population Reproductive medicine Fertilization in Vitro Clomiphene Gonadotropin-Releasing Hormone Ovulation Induction Genetics Humans Medicine Assisted Reproduction Technologies health care economics and organizations Genetics (clinical) Web based survey Retrospective Studies Fertility management Gynecology education.field_of_study business.industry Female infertility nutritional and metabolic diseases Obstetrics and Gynecology General Medicine medicine.disease female genital diseases and pregnancy complications Reproductive Medicine Treatment strategy Female business Infertility Female Gonadotropins Software Polycystic Ovary Syndrome Developmental Biology Demography |
| Zdroj: | Journal of Assisted Reproduction and Genetics. 30:1169-1174 |
| ISSN: | 1573-7330 1058-0468 |
| DOI: | 10.1007/s10815-013-0069-z |
| Popis: | To identify the leading treatment strategies for infertile women with PCOS on an international scale.A retrospective evaluation using the results of a web-based survey, (IVF-Worldwide ( www.IVF-worldwide.com ), posted from 1 to 30 September 2010 was performed. Binomial confidence intervals for proportions were calculated by the modified Wald method with significance defined as P 0.05 using a DataStar software package (DataStar, Waltham, MA, USA). Incomplete surveys were excluded from the analysis.The results from 262 centers in 68 nations were obtained. Clomiphene citrate was the clear first choice, 68 %, for PCOS treatment in the respondent group. Eighty-eight percent of respondents utilized ultrasound follicular monitoring when conducting ovulation induction with oral medications. A significant (p 0.05) proportion of respondents (66 %) did use some BMI cutoff beyond which IVF treatment was not offered. The preferred IVF protocols for PCOS patients were gonadotropin releasing hormone (GnRH) antagonist, 46 %, and GnRH agonist, 51 %. There was heterogeneity of responses observed regarding the management of a patient at very high risk of OHSS.While some advances, such as the use of GnRH antagonist regimen in IVF cycles, were relatively underutilized, the survey gives an unfiltered snapshot at the practice patterns of a large number of clinics. Results from this survey may be used by researchers and professional organizations to improve the clinical care of PCOS women suffering with infertility. |
| Databáze: | OpenAIRE |
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