Genetic and antigenic characterization of enterovirus 71 in Ho Chi Minh City, Vietnam, 2011
| Autor: | Truong Huu Khanh, Ih-Jen Su, Shu Ting Luo, Pai Shan Chiang, Le Nguyen Thanh Nhan, Tran Ngoc Hanh Dan, Ya Fang Wang, Than Duc Dung, Tang Chi Thuong, Le Quoc Thinh, Le Phan Kim Thoa, Jen Ren Wang, Min Shi Lee, Nguyen Thanh Hung, Wan Yu Chung |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Veterinary medicine
lcsh:Medicine Biology medicine.disease_cause Antigen Genotype Enterovirus Infections Enterovirus 71 medicine Humans lcsh:Science Antigens Viral Phylogeny Enterovirus Multidisciplinary Foot-and-mouth disease lcsh:R virus diseases Antigenic analysis biology.organism_classification medicine.disease Virology Ho chi minh Vietnam Vaccination policy lcsh:Q Research Article |
| Zdroj: | PLoS ONE, Vol 8, Iss 7, p e69895 (2013) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam. |
| Databáze: | OpenAIRE |
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