Thyroid-associated Orbitopathy: Quantitative Evaluation of the Orbital Fat Volume and Edema Using IDEAL-FSE

Autor: Haruya Ohno, Masayasu Yoneda, Kazuo Awai, Keizo Tanitame, Yuji Takahashi, Hideki Itakura, Yuji Akiyama, Hiroaki Terada, Yoko Kaichi
Rok vydání: 2019
Předmět:
lcsh:Medical physics. Medical radiology. Nuclear medicine
lcsh:R895-920
SI
signal intensity

water fraction
Article
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Orbital fat
Edema
Medicine
Radiology
Nuclear Medicine and imaging

In patient
orbital fat volume
IQR
interquartile range

Rank correlation
business.industry
TAO
thyroid-associated orbitopathy

proptosis
Thyroid
Healthy subjects
fast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimation (FSE-IDEAL)
FSE-IDEAL
fast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimation

thyroid-associated orbitopathy (TAO)
quantitative evaluation
medicine.anatomical_structure
030220 oncology & carcinogenesis
Mann–Whitney U test
medicine.symptom
Signal intensity
SD
standard deviation

business
Nuclear medicine
CAS
clinical activity score
Zdroj: European Journal of Radiology Open, Vol 6, Iss, Pp 182-186 (2019)
European Journal of Radiology Open
ISSN: 2352-0477
Popis: Background and Purpose: To compare orbital quantitative data obtained by fast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimation (FSE-IDEAL) in patients with thyroid-associated orbitopathy (TAO) and healthy controls and to investigate the characteristics of these data in TAO patients. Materials and Methods: Twenty-two TAO patients (4 males and 18 females; median age 51.0 years) and 22 healthy subjects (5 males and 17 females; median age 50.5 years) underwent orbital T2-weighted FSE-IDEAL. The water fraction in orbital fat was defined as the signal intensity (SI) water / (SI water + SI fat). The orbital fat volume was measured on fat images. The degree of proptosis was evaluated using in-phase imaging. Mann–Whitney U test was used to compare these quantitative data in the two groups. In TAO patients we ascertained the correlation among these values with the Spearman's rank correlation coefficient. Results: In TAO patients, the water fraction (right and left, p = 0.04), fat volume (right and left, p = 0.03) and degree of proptosis (right and left, p
Databáze: OpenAIRE