Thyroid-associated Orbitopathy: Quantitative Evaluation of the Orbital Fat Volume and Edema Using IDEAL-FSE
Autor: | Haruya Ohno, Masayasu Yoneda, Kazuo Awai, Keizo Tanitame, Yuji Takahashi, Hideki Itakura, Yuji Akiyama, Hiroaki Terada, Yoko Kaichi |
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Rok vydání: | 2019 |
Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
lcsh:R895-920 SI signal intensity water fraction Article 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Orbital fat Edema Medicine Radiology Nuclear Medicine and imaging In patient orbital fat volume IQR interquartile range Rank correlation business.industry TAO thyroid-associated orbitopathy proptosis Thyroid Healthy subjects fast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimation (FSE-IDEAL) FSE-IDEAL fast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimation thyroid-associated orbitopathy (TAO) quantitative evaluation medicine.anatomical_structure 030220 oncology & carcinogenesis Mann–Whitney U test medicine.symptom Signal intensity SD standard deviation business Nuclear medicine CAS clinical activity score |
Zdroj: | European Journal of Radiology Open, Vol 6, Iss, Pp 182-186 (2019) European Journal of Radiology Open |
ISSN: | 2352-0477 |
Popis: | Background and Purpose: To compare orbital quantitative data obtained by fast spin-echo iterative decomposition of water and fat with echo asymmetry and least-squares estimation (FSE-IDEAL) in patients with thyroid-associated orbitopathy (TAO) and healthy controls and to investigate the characteristics of these data in TAO patients. Materials and Methods: Twenty-two TAO patients (4 males and 18 females; median age 51.0 years) and 22 healthy subjects (5 males and 17 females; median age 50.5 years) underwent orbital T2-weighted FSE-IDEAL. The water fraction in orbital fat was defined as the signal intensity (SI) water / (SI water + SI fat). The orbital fat volume was measured on fat images. The degree of proptosis was evaluated using in-phase imaging. Mann–Whitney U test was used to compare these quantitative data in the two groups. In TAO patients we ascertained the correlation among these values with the Spearman's rank correlation coefficient. Results: In TAO patients, the water fraction (right and left, p = 0.04), fat volume (right and left, p = 0.03) and degree of proptosis (right and left, p |
Databáze: | OpenAIRE |
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