Effectiveness of correction of bleomycin-induced lung injury by early and late administration of surfactant-BL

Autor:	V. A. Serzhanina, A. A. Seiliev, V. A. Volchkov, O. A. Rosenberg, O. V. Klestova, V. F. Dubrovskaya, A. A. Valkovich
Rok vydání:	2012
Předmět:	Pathology medicine.medical_specialty Time Factors Fibrillar Collagens Lung injury Bleomycin General Biochemistry Genetics and Molecular Biology Drug Administration Schedule chemistry.chemical_compound Pulmonary surfactant Administration Inhalation medicine Leukocytes Animals Pulmonary pathology Lung Inhalation business.industry Macrophages Pulmonary Surfactants General Medicine Lung Injury respiratory system medicine.disease Rats medicine.anatomical_structure chemistry Cattle Lung tissue business
Zdroj:	Bulletin of experimental biology and medicine. 152(5)
ISSN:	1573-8221
Popis:	Rats were exposed to inhalation of surfactant-BL starting from the first or eighth day after intratracheal administration of bleomycin. At the early stages, the preparation effectively attenuated damage to ultrastructural components of the lung tissue and reduced the severity and extent of subsequent pulmonary pathology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d680a25da14ab74617ab236d3ac24219 https://pubmed.ncbi.nlm.nih.gov/22803138 Zobrazit plný text záznamu Full text from SpringerLink