Microbial Content of Nonsterile Therapeutic Agents Containing Natural or Seminatural Active Ingredients
| Autor: | A. Wolff, H. Kuntscher, M. Nekola, I. Schiller |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Preservative
Drug Industry Pharmacognosy Thyroid Gland Pancreatic Extracts Penicillins Microbial contamination Biology Microbiology Animal origin General Biochemistry Genetics and Molecular Biology Refrigeration Methods Pharmaceutic Aids Food science General Pharmacology Toxicology and Pharmaceutics Active ingredient Digitalis Plants Medicinal Bacteria General Immunology and Microbiology business.industry Pilocarpine Sterilization Articles General Medicine Contamination Sterilization (microbiology) Animal Organs Biotechnology Plants Toxic Pharmaceutical Preparations business |
| Zdroj: | Applied Microbiology. 16:1924-1928 |
| ISSN: | 0003-6919 |
| DOI: | 10.1128/am.16.12.1924-1928.1968 |
| Popis: | The relationship was investigated between various chemical or pharmaceutical production processes and the extent of microbial contamination, of natural origin, of the resulting products. The products contained active ingredients of vegetable, enzymatic, or animal origin. It was concluded that (i) vegetable products practically free from microbes can be produced if the proper manufacturing steps are taken; (ii) sterilization of the media used to manufacture antibiotics, etc., produces products with little contamination; and (iii) products containing extracts of animal organs require careful refrigeration and addition of preservatives to produce acceptable levels of microbial contamination. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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